2024
2023
Shee S, Veetil RT, Mohanraj K, Das M, Malhotra N, Bandopadhyay D, Beig H, Birua S, Niphadkar S, Nagarajan SNarayanan, Sinha VKumar, Thakur C, Rajmani RS, Chandra N, Laxman S, Singh M, Samal A, Seshasayee AN, Singh A.
2023. Biosensor-integrated transposon mutagenesis reveals as a coordinator of redox homeostasis in .. Elife. 12 DOI:10.7554/eLife.80218.
Das M, Sreedharan S, Shee S, Malhotra N, Nandy M, Banerjee U, Kohli S, Rajmani RS, Chandra N, Seshasayee ASai Narain, Laxman S, Singh A.
2023. Cysteine desulfurase (IscS)-mediated fine-tuning of bioenergetics and SUF expression prevents hypervirulence.. Sci Adv. 9(50):eadh2858. DOI:10.1126/sciadv.adh2858.
Prasad A, Sreedharan S, Bakthavachalu B, Laxman S.
2023. Eggs of the mosquito Aedes aegypti survive desiccation by rewiring their polyamine and lipid metabolism.. PLoS Biol. 21(10):e3002342. DOI:10.1371/journal.pbio.3002342.
Singh G, George G, Raja SO, Kandaswamy P, Kumar M, Thutupalli S, Laxman S, Gulyani A.
2023. A molecular rotor FLIM probe reveals dynamic coupling between mitochondrial inner membrane fluidity and cellular respiration.. Proc Natl Acad Sci U S A. 120(24):e2213241120. DOI:10.1073/pnas.2213241120.
2022
Saini N, Naaz A, Metur SPadma, Gahlot P, Walvekar A, Dutta A, Davathamizhan U, Sarin A, Laxman S.
2022. Methionine uptake via the SLC43A2 transporter is essential for regulatory T-cell survival.. Life Sci Alliance. 5(12) DOI:10.26508/lsa.202201663.
Tripathi A, Anand K, Das M, O'Niel RAnnie, S SP, Thakur C, L RReddy R, Rajmani RS, Chandra N, Laxman S, Singh A.
2022. Mycobacterium tuberculosis requires SufT for Fe-S cluster maturation, metabolism, and survival in vivo.. PLoS Pathog. 18(4):e1010475. DOI:10.1371/journal.ppat.1010475.
Bandyopadhyay P, Pramanick I, Biswas R, Ps S, Sreedharan S, Singh S, Rajmani RS, Laxman S, Dutta S, Singh A.
2022. S-Adenosylmethionine-responsive cystathionine β-synthase modulates sulfur metabolism and redox balance in Mycobacterium tuberculosis .. Sci Adv. 8(25):eabo0097. DOI:10.1126/sciadv.abo0097.
2021
Laxman S.
2021. The bacterial social network and beyond.. Nat Rev Mol Cell Biol. 22(7):443. DOI:10.1038/s41580-021-00369-3.
Varahan S, Laxman S.
2021. Bend or break: how biochemically versatile molecules enable metabolic division of labor in clonal microbial communities.. Genetics. 219(2) DOI:10.1093/genetics/iyab109.
2020
Bhatia M, Thakur J, Suyal S, Oniel R, Chakraborty R, Pradhan S, Sharma M, Sengupta S, Laxman S, Masakapalli SKumar, Bachhawat AKumar.
2020. Allosteric inhibition of MTHFR prevents futile SAM cycling and maintains nucleotide pools in one-carbon metabolism.. J Biol Chem. 295(47):16037-16057. DOI:10.1074/jbc.RA120.015129.
Shaw E, Talwadekar M, Rashida Z, Mohan N, Acharya A, Khatri S, Laxman S, Kolthur-Seetharam U.
2020. Anabolic SIRT4 Exerts Retrograde Control over TORC1 Signaling by Glutamine Sparing in the Mitochondria.. Mol Cell Biol. 40(2) DOI:10.1128/MCB.00212-19.
Srinivasan R, Walvekar AS, Rashida Z, Seshasayee A, Laxman S.
2020. Genome-scale reconstruction of Gcn4/ATF4 networks driving a growth program.. PLoS Genet. 16(12):e1009252. DOI:10.1371/journal.pgen.1009252.
Walvekar AS, Kadamur G, Sreedharan S, Gupta R, Srinivasan R, Laxman S.
2020. Methylated PP2A stabilizes Gcn4 to enable a methionine-induced anabolic program.. J Biol Chem. DOI:10.1074/jbc.RA120.014248.
Walvekar AS, Kadamur G, Sreedharan S, Gupta R, Srinivasan R, Laxman S.
2020. Methylated PP2A stabilizes Gcn4 to enable a methionine-induced anabolic program.. J Biol Chem. 295(52):18390-18405. DOI:10.1074/jbc.RA120.014248.
Negi H, Reddy PPurushotha, Vengayil V, Patole C, Laxman S, Das R.
2020. A novel polyubiquitin chain linkage formed by viral Ubiquitin is resistant to host deubiquitinating enzymes.. Biochem J. 477(12):2193-2219. DOI:10.1042/BCJ20200289.
Bruhn C, Ajazi A, Ferrari E, Lanz MCharles, Batrin R, Choudhary R, Walvekar A, Laxman S, Longhese MPia, Fabre E, Smolka MBustamente, Foiani M.
2020. The Rad53-Spt21 and Tel1 axes couple glucose tolerance to histone dosage and subtelomeric silencing.. Nat Commun. 11(1):4154. DOI:10.1038/s41467-020-17961-4.
2019
Vengayil V, Rashida Z, Laxman S.
2019. The E3 ubiquitin ligase Pib1 regulates effective gluconeogenic shutdown upon glucose availability.. J Biol Chem. DOI:10.1074/jbc.RA119.009822.
Varahan S, Walvekar A, Sinha V, Krishna S, Laxman S.
2019. Metabolic constraints drive self-organization of specialized cell groups.. Elife. 8 DOI:10.7554/eLife.46735.
Walvekar AS, Laxman S.
2019. Methionine at the Heart of Anabolism and Signaling: Perspectives From Budding Yeast.. Front Microbiol. 10:2624. DOI:10.3389/fmicb.2019.02624.
2018
Walvekar AS, Srinivasan R, Gupta R, Laxman S.
2018. Methionine coordinates a hierarchically organized anabolic program enabling proliferation.. Mol Biol Cell. :mbcE18080515. DOI:10.1091/mbc.E18-08-0515.
Krishna S, Laxman S.
2018. A minimal "push-pull" bistability model explains oscillations between quiescent and proliferative cell states.. Mol Biol Cell. 29(19):2243-2258. DOI:10.1091/mbc.E18-01-0017.
Walvekar A, Rashida Z, Maddali H, Laxman S.
2018. A versatile LC-MS/MS approach for comprehensive, quantitative analysis of central metabolic pathways.. Wellcome Open Res. 3:122. DOI:10.12688/wellcomeopenres.14832.1.
2017
Laxman S.
2017. Conceptualizing Eukaryotic Metabolic Sensing and Signaling.. J Indian Inst Sci. 97(1):59-77. DOI:10.1007/s41745-016-0013-1.
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