Export 4 results:
Author Title Type [ Year(Asc)]
Filters: Keyword is Hematopoietic Stem Cells and Author is Thangavel, Saravanabhavan  [Clear All Filters]
2024
Rajendiran V, Devaraju N, Haddad M, Ravi NSam, Panigrahi L, Paul J, Gopalakrishnan C, Wyman S, Ariudainambi K, Mahalingam G, Periyasami Y, Prasad K, George A, Sukumaran D, Gopinathan S, Pai AAnand, Nakamura Y, Balasubramanian P, Ramalingam R, Thangavel S et al..  2024.  Base editing of key residues in the BCL11A-XL-specific zinc finger domains derepresses fetal globin expression.. Mol Ther. 32(3):663-677. DOI:10.1016/j.ymthe.2024.01.023.
2022
Venkatesan V, Christopher ACrystal, Karuppusamy KV, Babu P, Alagiri MKumar K, Thangavel S.  2022.  CRISPR/Cas9 Gene Editing of Hematopoietic Stem and Progenitor Cells for Gene Therapy Applications.. J Vis Exp. (186) DOI:10.3791/64064.
Ravi NSam, Wienert B, Wyman SK, Bell HWilliam, George A, Mahalingam G, Vu JT, Prasad K, Bandlamudi BPrasad, Devaraju N, Rajendiran V, Syedbasha N, Pai AAnand, Nakamura Y, Kurita R, Narayanasamy M, Balasubramanian P, Thangavel S, Marepally S, Velayudhan SR et al..  2022.  Identification of novel HPFH-like mutations by CRISPR base editing that elevate the expression of fetal hemoglobin.. Elife. 11 DOI:10.7554/eLife.65421.
Christopher ACrystal, Venkatesan V, Karuppusamy KV, Srinivasan S, Babu P, Azhagiri MKumar K, Chambayil K, Bagchi A, Rajendiran V, Ravi NSam, Kumar S, Marepally SKumar, Mohankumar KMurugesan, Srivastava A, Velayudhan SR, Thangavel S.  2022.  Preferential Expansion of Human CD34CD133CD90 Hematopoietic Stem Cells Enhances Gene-Modified Cell Frequency for Gene Therapy.. Hum Gene Ther. 33(3-4):188-201. DOI:10.1089/hum.2021.089.