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Author Title Type [ Year(Desc)]
Filters: Author is Rajendiran, Vignesh and Keyword is Gene Editing  [Clear All Filters]
2022
Devaraju N, Rajendiran V, Ravi NSam, Mohankumar KM.  2022.  Genome Engineering of Hematopoietic Stem Cells Using CRISPR/Cas9 System.. Methods Mol Biol. 2429:307-331. DOI:10.1007/978-1-0716-1979-7_20.
Ravi NSam, Wienert B, Wyman SK, Bell HWilliam, George A, Mahalingam G, Vu JT, Prasad K, Bandlamudi BPrasad, Devaraju N, Rajendiran V, Syedbasha N, Pai AAnand, Nakamura Y, Kurita R, Narayanasamy M, Balasubramanian P, Thangavel S, Marepally S, Velayudhan SR et al..  2022.  Identification of novel HPFH-like mutations by CRISPR base editing that elevate the expression of fetal hemoglobin.. Elife. 11 DOI:10.7554/eLife.65421.
2024
Rajendiran V, Devaraju N, Haddad M, Ravi NSam, Panigrahi L, Paul J, Gopalakrishnan C, Wyman S, Ariudainambi K, Mahalingam G, Periyasami Y, Prasad K, George A, Sukumaran D, Gopinathan S, Pai AAnand, Nakamura Y, Balasubramanian P, Ramalingam R, Thangavel S et al..  2024.  Base editing of key residues in the BCL11A-XL-specific zinc finger domains derepresses fetal globin expression.. Mol Ther. 32(3):663-677. DOI:10.1016/j.ymthe.2024.01.023.