Computational medicinal chemist

JOB DESCRIPTION:

IN THIS POSITION YOU WILL SUPPORT CHEMICAL BIOLOGY EFFORTS UNDERPINNING
NEW LEAD DISCOVERY BY PROVIDING COMPUTATIONAL EXPERTISE INCLUDING, BUT
NOT LIMITED TO THE FOLLOWING;

  • Apply computational chemistry tools to
    • Evaluate and analyze targets of interest for druggability/ligandability
    • Identify and design hits for challenging/novel targets of interest
    • Develop and optimize hits for potency and selectivity
  • Work with interdisciplinary teams seamlessly to drive drug discovery projects
  • Independently plan, execute and deliver results in a timely fashion
  • Regular data analysis, project updates, literature survey and presentations on the targets
  •  Participate in project team meetings and contribute to the projects intellectually
  • Must be detail oriented, well organized with ability to analyze and communicate data effectively
  • Must be a team player in a fast-paced, multi-disciplinary environment
  • Maintain servers, software and databases

REQUIREMENTS:

  • PhD in Medicinal Chemistry/Computational Chemistry/other relevant fields with more than 4 years of experience OR Masters/M.E in Medicinal Chemistry/Pharmaceutical Chemistry/other relevant fields with more than 8 years of experience in the application of computational tools to facilitate the design and optimization of potent and selective small molecules against various targets of interest.
  • Knowledge of the latest technologies in computational chemistry, and openness to explore new methods for drug discovery
  • Competence in structure-based and ligand-based design techniques like protein modelling, virtual screening, SAR, molecular dynamics simulations, etc., is critical
  • Scripting skills are preferred.
  • Experience in working independently and managing team member

HOW TO APPLY:  Interested candidates may send in the following information by email to jobs-ccbt@instem.res.in

  • Curriculum Vitae (CV) 
  • Publication list 
  • Contact details of three professional referees
  • Specify "Computational Chemistry" and your designation in the subject line of your email
Status of Position: Open