Dr. Sudarshan Gadadhar - Publications
Key publications
Gadadhar, Sˆ., Hirschmugl, T., & Janke, Cˆ. (2022). The tubulin code in mammalian sperm development and function. Seminars in Cell and Developmental Biology. https://doi.org/10.1016/j.semcdb.2021.12.003 ˆco-corresponding author
Gadadhar, Sˆ., Viar, G. A., Hansen, J. N., Gong, A., Kostarev, A., Ialy-Radio, C., Leboucher, S., Whitfield, M., Ziyyat, A., Touré, A., Alvarez, Lˆ., Pigino, Gˆ., & Janke, Cˆ. (2021). Tubulin glycylation controls axonemal dynein activity, flagellar beat, and male fertility. Science, 371(6525). https://doi.org/10.1126/science.abd4914ˆco-corresponding author, highlighted on the cover of Science
Bodakuntla, S., Yuan, X., Genova, M., Gadadhar, S., Leboucher, S., Birling, M.-C., Klein, D., Martini, R., Janke, C., & Magiera, M. M. (2021). Distinct roles of α- and β-tubulin polyglutamylation in controlling axonal transport and in neurodegeneration. EMBO Journal, 40(17). https://doi.org/10.15252/embj.2021108498
Giordano, T*., Gadadhar, S*., Bodakuntla, S., Straub, J., Leboucher, S., Martinez, G., Chemlali, W., Bosc, C., Andrieux, A., Bieche, I., Arnoult, C., Geimer, S., & Janke, C. (2019). Loss of the deglutamylase CCP5 perturbs multiple steps of spermatogenesis and leads to male infertility. Journal of Cell Science, 132(3). https://doi.org/10.1242/jcs.226951 *equal contribution
Magiera, M. M., Singh, P., Gadadhar, S., & Janke, C. (2018). Tubulin Posttranslational Modifications and Emerging Links to Human Disease. Cell, 173(6), 1323–1327. https://doi.org/10.1016/j.cell.2018.05.018
Gadadhar, S., Dadi, H., Bodakuntla, S., Schnitzler, A., Bièche, I., Rusconi, F., & Janke, C. (2017). Tubulin glycylation controls primary cilia length. Journal of Cell Biology, 216(9), 2701–2713. https://doi.org/10.1083/jcb.201612050
Gadadhar, S., Bodakuntla, S., Natarajan, K., & Janke, C. (2017). The tubulin code at a glance. Journal of Cell Science, 130(8), 1347–1353. https://doi.org/10.1242/jcs.199471
Natarajan, K., Gadadhar, S., Souphron, J., Magiera, M. M., & Janke, C. (2017). Molecular interactions between tubulin tails and glutamylases reveal determinants of glutamylation patterns. EMBO Reports, 18(6), 1013–1026. https://doi.org/10.15252/embr.201643751
Grau, M. B., Masson, C., Gadadhar, S., Rocha, C., Tort, O., Sousa, P. M., Vacher, S., Bieche, I., & Janke, C. (2017). Alterations in the balance of tubulin glycylation and glutamylation in photoreceptors leads to retinal degeneration. Journal of Cell Science, 130(5), 938–949. https://doi.org/10.1242/jcs.199091