Dr. Srinivasarao Repudi - Publications
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Repudi S, Irina K, Sara AS, Shani S, *Aqeilan RI.. Neonatal neuronal WWOX gene therapy rescues Wwox null phenotypes. EMBO Molecular Medicine, (2021), 13 (12), e14599 (selected for journal cover page, volume 13, issue 12, Dec 7, 2021).
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Steinberg DJ, Repudi S, Saleem A, Kustanovich I, Viukov S, Abudiab B, Banne E, Mahajnah M, Hanna JH, Stern S, Carlen PL, *Aqeilan RI. Modeling genetic epileptic encephalopathies using brain organoids. EMBO Molecular Medicine, (2021), 13 (8), e13610.
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Repudi S, Steinberg DJ, Elazar N, Breton VL, Aquilino MS, Saleem A, Abu-Swai S, Vainshtein A, Eshed-Eisenbach Y, Vijayaragavan B, Behar O, Hanna JH, Peles E, Carlen PL, Aqeilan RI. Wwox deletion in neurons, linked to WOREE syndrome, leads to epilepsy and myelin abnormalities. Brain, (2021), 144, 3061-3077
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Breton VL, Aquilino MS, Repudi S, Saleem A, Mylvaganam S, Abu-Swai S, Bardakjian BL, Aqeilan RI, Carlen PL. Altered neocortical oscillations and cellular excitability in an in vitro Wwox knockout mouse model of epileptic encephalopathy. Neurobiology of Disease, (2021), 160, 105529.
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Repudi S, Milan Patra and *Malini Sen. WISP3 - IGF1 Interaction Regulates Chondrocyte Hypertrophy. Journal of Cell Science, 2013 126 (7):1650-1658.
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Karthika RU, Repudi S, Sahoo S, *Prashanth K. Phenotypic and genotypic assays for detecting the prevalence of metallo-betalactamases in clinical isolates of Acinetobacter baumannii from a south Indian tertiary care hospital. Journal of Medical Microbiology, (2009) 58: 430–435.
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Repudi S, Karthika RU, Singh SP, Shashikala P, Kanungo R, Jayachandran S, *Prashanth K. Correlation between biofilm production and multiple drug resistance in imipenem resistant clinical isolates of Acinetobacter baumannii. Indian Journal of Medical Microbiology, (2008) 26: 333-337.
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John J, Saranathan R, Adigopula LN, Thamodharan V, Singh SP, Lakshmi TP, Charan Tej MA, Repudi S, Krishna R, Rao HS, *Prashanth K. The quorum sensing molecule N-acyl homoserine lactone produced by Acinetobacter baumannii displays antibacterial and anticancer properties. Biofouling, (2016) 32:1029-47.
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Banne E, Abudiab B, Abu-Swai S, Repudi S, Steinberg DJ, Shatleh D, Alshammery S, Lisowski L, Gold W, Carlen PL, Aqeilan RI. Neurological Disorders Associated with WWOX Germline Mutations—A Comprehensive Overview. Cells, (2021), 10: 824.
PATENT
AAV mediated WWOX delivery a method for the treatment of WWOX associated epileptic encephalopathies (US-PCT ref 70-078)