Department of Biotechnology
inStem (Institute for Stem Cell Science and Regenerative Medicine)

Generation of control human iPSC line INSTEMi001-A from PBMCs of a healthy Indian donor.

Publication Type

Journal Article

Date of Publication

June 1, 2023

Journal

Stem cell research

Volume/Issue

69

ISSN

1876-7753

Human pluripotent stem cells serve as a robust model system to study disease pathogenesis in a dish and search for various targeted therapeutics. Collection of control lines from healthy individuals are essential for any study. Therefore, we have generated hiPSC line from a healthy male donor after episomal reprogramming of PBMCs. The generated line is pluripotent, had normal karyotype and has a potential of tri-lineage differentiation. The generated line would serve as control line of Asian origin from Indian population.

Alternate Journal

Stem Cell Res

PubMed ID

37236122

Authors

Niharika Patlolla
Pretty Ponnachan
Colin Jamora
Deepti Abbey

Keywords

Plasmids
Leukocytes, Mononuclear
Cellular Reprogramming
Asian People
Cell Differentiation
Male
Humans
Induced Pluripotent Stem Cells
Cell Line