Department of Biotechnology
inStem (Institute for Stem Cell Science and Regenerative Medicine)

Chemical fuel-driven living and transient supramolecular polymerization.

Publication Type

Research Support, Non-U.S. Gov't

Date of Publication

January 25, 2019

Journal

Nature communications

Volume/Issue

10/1

ISSN

2041-1723

Temporal control over self-assembly process is a desirable trait in the quest towards adaptable and controllable materials. The ability to devise synthetic ways to control the growth, as well as decay of materials has long been a property which only the biological systems could perform seamlessly. A common synthetic strategy which works on the biological principles such as chemical fuel-driven control over temporal self-assembly profile has not been completely realized synthetically. Here we show, we filled this dearth by showing that a chemical fuel driven self-assembling system can not only be grown in a controlled manner, but it can also result in precise control over the assembly and disassembly kinetics. Herein, we elaborate strategies which clearly show that once a chemical fuel driven self-assembly is established it can be made receptive to multiple molecular cues such that the inherent growth and decay characteristics are programmed into the ensemble.

Alternate Journal

Nat Commun

PubMed ID

30683874

PubMed Central ID

PMC6347607

Authors

Ankit Jain
Shikha Dhiman
Ashish Dhayani
Praveen K Vemula
Subi J George