inStem (Institute for Stem Cell Science and Regenerative Medicine)
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179 Articles found
TIGS and inStem join hands to work on rare genetic diseases
Scientific breakthroughs from the last few decades have now made it possible for us to explore cures and treatments that were once considered impossible. With the help of these innovations it may soon become possible to alleviate the many challenges and sufferings faced by millions of people who suffer from rare diseases. Rare diseases, […]
Sense of smell regulates and develops immune system in flies
The immune system consists of cells, tissues, organs, etc. that work as a team to fight off illness, infections and other invaders. When an unsafe substance enters the body, the immune system comes to the fore and launches an attack. Olfaction or the sense of smell is a sense through which odors are perceived and […]
Mapping the unMAP’d
A team of researchers from Curie Institute, Orsay in collaboration with DBT-inStem, Bangalore report characterization of ~50 microtubule-associated proteins (called MAPs) in an unprecedented detail. Microtubules are miniature tubes like filaments in cells (microtubule diameter is 25 nanometer; 1 nanometer is one-billionth of a meter). They are important in transport of molecules within cells (Cells […]
Dr. Sunil Laxman receives the DBT-Wellcome Trust India Alliance Senior Research Fellowship
Blast from the Past: A Rippled Tapestry of Genetic Variation May Predispose Humans to Mental Illness
Research by scientists and clinicians from NIMHANS and the ADBS program, DBT-inStem, Bangalore, India and Tartu, Estonia underscores the fact that the common syndromes of severe mental illness, such as schizophrenia, bipolar disorder, dementia, obsessive compulsive disorder and addiction, may have an unusual evolutionary basis. The constant prevalence of mental illness, across the history of […]
Communication between Skin Epithelial Cells and Macrophages Sets Up Sterile Inflammation
Skin is the largest and the outermost organ of the body and serves as a barrier from the external environment. It has two compartments – the epidermis and dermis. The two compartments are separated by an array of extracellular matrix (ECM) components known as the basement membrane (BM). The ECM is a meshwork of macromolecules […]
TORC1 and AMPK Work Together to Manage Carbon Homeostasis in Changing Nutrient Environments
Cells naturally experience fluctuating nutrient conditions. To adapt and grow in such conditions, cells precisely balance the allocation of available nutrients through finely regulated metabolism. This regulation occurs through the functioning of nutrient responsive signaling-systems. The two important signaling complexes in all eukaryotes that regulate nutrient utilization and cell growth are target of rapamycin (TORC1) […]
One Year of the COVID Testing Centre: A Bittersweet Experience
The COVID-19 pandemic has had a devastating impact on global public health with crippling socioeconomic consequences. The goal of containing the spread of SARS-CoV-2 – the virus causing COVID-19 still relies on a comprehensive strategy of rapid testing of the virus in the population, effective treatments, and the development of therapeutics to prevent the spread […]
