inStem (Institute for Stem Cell Science and Regenerative Medicine)
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Baker’s yeast teaches us how to budget during a crisis
They brew your beer and bloat your bread. They inhabit the skin of fruits and colonize some of the deepest parts of the human body. Say hello to the whiz kid of the fungal kingdom, Saccharomyces cerevisiae, commonly referred to as baker’s yeast. Image: Control of metabolic specialization by Aspartate Highly versatile and quick to […]
CNS,inStem – NYU Researchers Develop Method to Identify Newly Synthesized Proteins in Blood
CNS, inStem – NYU Researchers Develop Method to Identify Newly Synthesized Proteins in Blood We have all had blood tests in our lives that involved drawing a small quantity of blood from our veins and testing it for the levels of enzymes, vitamins, iron, and glucose. The blood draw remains the most commonly used biopsy […]
The Immune System in Growth Control
The regulation of growth in animals continues to intrigue scientists. In order to breakdown and understand the many elements that control growth, scientists turn to biological systems where it is possible to track different stages of development, all the way from the earliest stages of formation to an adult fully grown organism in the laboratory. […]
SARS-CoV-2 genome sequencing effort
COVID-19 response by scientists at DBT-inStem and NCBS-TIFR, Bengaluru COVID-19, the disease caused by the SARS-CoV-2 virus, is an ongoing pandemic, affecting millions of people worldwide, with lakhs of cases in India. Sequencing viral genomes from infected individuals across the country can help understand transmission chains, the dynamics of the global pandemic and viral genome […]
Autism in a Dish
Autism Spectrum Disorders and Intellectual Disabilities (ASD/IDs) represent a major and growing public health challenge. The Department of Biotechnology (DBT) supported the Centre for Neurodevelopmental Synaptopathies (CNS) – a partnership between inStem and NCBS in Bangalore and the University of Edinburgh, UK – to study the pathophysiology of ASD/IDs. A major effort at the CNS […]
Resolving Actin Filament Cell Illuminators with cryo-EM
Actin filaments are one class of cytoskeleton filaments that provide structural framework to cells. The cytoskeleton filament structures are analogous to the scaffolds and columns of a building. However, the cytoskeleton filaments are very dynamic and undergo remodelling in major part of a cell’s life span. Because of their important role in physiology, any deficits […]
Casting a Long Shadow: The Consequences of Adverse Childhood Experiences
Adverse Childhood Experiences (ACEs) are distressing experiences that occur during early life, and may have far reaching consequences impacting adulthood. These experiences include various forms of abuse and neglect, both physical and/or emotional. In addition, they also include trauma experienced by communities such as war, terrorism, and other forms of community violence. Research in the […]
Behind the Scenes of the BLiSc Testing Effort: About Our Contributors
The COVID-19 pandemic is upon us! The nation has been through prolonged lockdowns, yet the rising case numbers, has kept up the relentless demand on testing. The scientific community at the BLiSc campus rose to the need of the hour and by early April, operationalized an efficient sample testing laboratory. The testing laboratory since […]
