inStem (Institute for Stem Cell Science and Regenerative Medicine)
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176 Articles found
Autism in a Dish
Autism Spectrum Disorders and Intellectual Disabilities (ASD/IDs) represent a major and growing public health challenge. The Department of Biotechnology (DBT) supported the Centre for Neurodevelopmental Synaptopathies (CNS) – a partnership between inStem and NCBS in Bangalore and the University of Edinburgh, UK – to study the pathophysiology of ASD/IDs. A major effort at the CNS […]
Resolving Actin Filament Cell Illuminators with cryo-EM
Actin filaments are one class of cytoskeleton filaments that provide structural framework to cells. The cytoskeleton filament structures are analogous to the scaffolds and columns of a building. However, the cytoskeleton filaments are very dynamic and undergo remodelling in major part of a cell’s life span. Because of their important role in physiology, any deficits […]
Casting a Long Shadow: The Consequences of Adverse Childhood Experiences
Adverse Childhood Experiences (ACEs) are distressing experiences that occur during early life, and may have far reaching consequences impacting adulthood. These experiences include various forms of abuse and neglect, both physical and/or emotional. In addition, they also include trauma experienced by communities such as war, terrorism, and other forms of community violence. Research in the […]
Behind the Scenes of the BLiSc Testing Effort: About Our Contributors
The COVID-19 pandemic is upon us! The nation has been through prolonged lockdowns, yet the rising case numbers, has kept up the relentless demand on testing. The scientific community at the BLiSc campus rose to the need of the hour and by early April, operationalized an efficient sample testing laboratory. The testing laboratory since […]
The COVID-19 Testing Effort at the Bangalore Life Science Cluster
Ten thousand and counting… The SARS-CoV-2 testing pipeline at the testing laboratory of the Bangalore Life Science Cluster “The testing effort on campus is rooted in our community’s commitment to respond to national need.” – Apurva Sarin, Director, inStem We all remember the early days when the news of the COVID-19 pandemic was being discussed […]
Covid-Gyan website
This website serves as a hub to bring together a collection of resources in response to the COVID-19 outbreak. These resources are generated by public supported research institutions in India and associated programs. The content presented here relies on the best available scientific understanding of the disease and its transmission.
Energy Budgeting in the Brain: Protein Synthesis Takes the Lion’s Share
The adult human brain is an amazing organ that forms the primary part of the central nervous system along with the spinal cord and nerves that run throughout our body. Apart from controlling all functions of our body, the brain also interprets information from the outside world through the five senses, often all at one […]
inStem Neuroscientists’ Finding of Inherited Mutations in S6 Kinase 1 from Parents can Change Autism Severity
Autism spectrum disorder (ASD) or Autism as it is commonly called, is a major cause of developmental delay that is usually diagnosed in children between 6 months to 5 years age. The condition mainly shows up as an impairment of language, social interaction and non-verbal behaviour, not the least compulsive interests that a child insists […]
