Department of Biotechnology
inStem (Institute for Stem Cell Science and Regenerative Medicine)

Type 5 Diabetes- The Rejuvenated Spirit from a Ghost of the Past.

Publication Type

Journal Article

Date of Publication

August 8, 2025

Journal

Indian journal of endocrinology and metabolism

Volume/Issue

29/3

ISSN

2230-8210

Diabetes is a less than divine scourge that envelops the planet, by and large induced by an ignominious conglomeration encompassing a multitude of factors involving lifestyle alteration. It transcends socioeconomic boundaries, and its prevalence has skyrocketed worldwide. Ever since the World Health Organisation (WHO) first classified diabetes mellitus (DM) in 1965, the understanding and categorisation of this disease have evolved with multiple paradigm shifts, involving several alterations over a period of the past 3 score years. More notably, in 1985, the classification system for diabetes mellitus gained widespread clinical acceptance, introducing a new category: malnutrition-related diabetes mellitus (MRDM). This condition, which was initially noticed in Jamaica and also christened as J-type, K-type, or M-type diabetes, malnutrition diabetes, and ketosis-resistant youth-onset diabetes, had sparked considerable debate due to the lack of scientific evidence, leading to its erasure from the WHO classification in 1999. However, the dialogue regarding the presence of MRDM persisted into the current part of the third millennium.

Alternate Journal

Indian J Endocrinol Metab

PubMed ID

40688630

PubMed Central ID

PMC12274040

Authors

Jebasingh F
Thomas N