inStem (Institute for Stem Cell Science and Regenerative Medicine)

Research Publications

Identifying quantitative sncRNAs signature using global sequencing as a potential biomarker for tuberculosis diagnosis and their role in regulating host response.

Publication Type

Journal Article

Date of Publication

June 1, 2024

Journal

International journal of biological macromolecules

Volume/Issue

271/Pt 2

ISSN

1879-0003

The study aimed to identify a quantitative signature of circulating small non-coding RNAs (sncRNAs) as a biomarker for pulmonary tuberculosis disease (active-TB/ATB) and explore their regulatory roles in host-pathogen interactions and disease progression.

DOI

10.1016/j.ijbiomac.2024.132714

Alternate Journal

Int J Biol Macromol

PubMed ID

Authors

Sheetal Kaul

Vivek Nair

Lorna Gcanga

Vairavan Lakshmanan

M Kalamuddin

Vandana Anang

Sumit Rathore

Shikha Dhawan

Tanvir Alam

Vishal Khanna

Sheelu Lohiya

Shakir Ali

Shamim Mannan

Kirankumar Rade

Suraj P Parihar

Ashwani Khanna

Pawan Malhotra

Frank Brombacher

Palakodeti Vn Dasaradhi

Reto Guler

Asif Mohmmed

Keywords

High-Throughput Nucleotide Sequencing

Case-Control Studies

ROC Curve

Mycobacterium tuberculosis

Female

Male

Humans

Adult

Host-Pathogen Interactions

Biomarkers

Tuberculosis, Pulmonary

RNA, Small Untranslated

Middle Aged

MicroRNAs

Tuberculosis

Cross-Sectional Studies