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Major South Asian heart disease gene discovered

Our work on the molecular genetics of cardiomyopathies led to a major discovery as we unraveled an ancient Myosin Binding Protein c3 (MYBPC3) gene deletion as a major risk factor for South Asians. To date, approximately 60 million people carry the heterozygous deletion. This variant, in its homozygous nature, causes severe childhood cardiomyopathies. Of note, this discovery was the subject of a documentary by Dr. Sanjay Gupta of CNN.

Please click the youtube video shown below for more details.