About Us
Bridging disciplines. Unifying ideas.
The Institute for Stem Cell Biology and Regenerative Medicine (inStem), is a state-of-the-art research institute in Bangalore, India, dedicated to the study of stem cell and regenerative biology.
An autonomous institute funded by the Dept of Biotechnology, Govt. of India, inStem emphasizes collaborative research in stem cell biology. inStem’s mandate to allow this cross-disciplinary, multi-pronged approach to research, straddles the divide between clinical and laboratory research in stem cell biology. In trying to answer intractable and challenging questions that face the field, inStem seeks to rewrite the paradigm of the research institute: without barriers and across disciplines.
Research at inStem, encompasses a wide range of topics in stem cell biology: from questions about the fundamental mechanisms that control differentiation and renewal, to clinical studies on the impact of stem cells on recovery from stroke/injury. The institute is also home to the Wadhwani Centre, a generous philanthropic donation dedicated to the study of stem cell biology of the nervous system as well as cardiomyopathies. inStem’s fast-growing, young and enthusiastic atmosphere ensures that its work is at the very forefront of science.
Research
Research at inStem addresses the genetic mechanisms of potency, differentiation and proliferation in human pluripotent cells, examines clinical manifestations of diseases that can potentially be treated by stem cells, models human diseases using stem cells, uses model organisms such as Planaria and Hydra to address fundamental questions in regenerative biology, develops platforms to interrogate signaling pathways with new chemical entities, and finally, develops tools that will help to better understand the biology driving stem cells and eventually treat disease states.At inStem, research is primarily carried out by groups who work on tightly-knit themes, crossing boundaries and developing new approaches to address questions larger than the expertise of individual researchers.
Academics
inStem’s vibrant, enthusiastic and intellectual environment and its committed faculty provide a great environment for educational and training programs. Currently, programs exist to support postdocs, graduate students and project trainees. A key focus is the creation of a supportive environment for outstanding young investigators through a Fellows Program. inStem offers outstanding research facilities easily on par with the best in the world. With access to cutting-edge technologies, set in the centre of the country’s biotech hub and with exposure to leaders in science through seminars and workshops, inStem’s stimulating environment develops the best in young scientists. Researchers at inStem are continually exposed to new technologies.
News
"Microbe hunter" Ian Lipkin speaks on science and Hollywood
Recent Publications Highlights
- ACS Chem Biol., January 2014: Unique, polyfucosylated glycan-receptor interactions are essential for regeneration of Hydra magnipapillata.
- Biochem Biophys Res Commun., February 2014: Expression, purification and substrate specificities of 3-nitrotoluene dioxygenase from Diaphorobacter sp. strain DS2.
External Links
Reach Us
Institute for Stem Cell Biology and Regenerative Medicine,
National Centre for Biological Sciences,
Tata Institute of Fundamental Research,
GKVK, Bellary Road,
Bangalore 560065, India.