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Shared genetic link between obesity and cardiomyopathy

"We discovered a unique syndrome with cardiomyopathy and obesity. My interest lies in understanding the specific genetic etiology and functions attributed to the gene that causes this syndrome. This would pave the way to understanding novel inter-organ cross-talks that involve the heart, metabolism, and brain, thereby giving insight into its exciting biology. We aim to identify the novel pathological signaling involved using techniques ranging from whole exome sequencing, calcium imaging, and transgenic fly models to patient-derived cardiomyocytes. This study could pave the way for early diagnostics and personalized therapy."

Prasanth Chimata

PhD Student (GS-2017)