@article {2212,
	title = {Microneedles for Extended Transdermal Therapeutics: A Route to Advanced Healthcare.},
	journal = {Eur J Pharm Biopharm},
	volume = {159},
	year = {2021},
	month = {2021 Feb},
	pages = {151-169},
	abstract = {<p>Sustained release of drugs over a pre-determined period is required to maintain an effective therapeutic dose for variety of drug delivery applications. Transdermal devices such as polymeric microneedle patches and other microneedle-based devices have been utilized for sustained release of their payload. Swift clearing of drugs can be prevented either by designing a slow-degrading polymeric matrix or by providing physiochemical triggers to different microneedle-based devices for on-demand release. These long-acting transdermal devices prevent the burst release of drugs. This review highlights the recent advances of microneedle-based devices for sustained release of vaccines, hormones, and antiretrovirals with their prospective safe clinical translation.</p>
},
	issn = {1873-3441},
	doi = {10.1016/j.ejpb.2020.12.020},
	author = {Pahal, Suman and Badnikar, Kedar and Ghate, Vivek and Bhutani, Utkarsh and Nayak, Mangalore Manjunatha and Subramanyam, Dinesh Narasimhaiah and Vemula, Praveen Kumar}
}
