Research


Research at inStem addresses the genetic mechanisms of potency, differentiation and proliferation in human pluripotent cells, examines clinical manifestations of diseases that can potentially be treated by stem cells, models human diseases using stem cells, uses model organisms such as Planaria and Hydra to address fundamental questions in regenerative biology, develops platforms to interrogate signaling pathways with new chemical entities, and finally, develops tools that will help to better understand the biology driving stem cells and eventually treat disease states.At inStem, research is primarily carried out by groups who work on tightly-knit themes, crossing boundaries and developing new approaches to address questions larger than the expertise of individual researchers.

 

Themes & Teams

 

Centre for Brain Development and Repair

 

Center for Brain Development and Repair collaborates with labs at the University of Edinburgh to understand autism spectrum disorders.

Sumantra Chattarji(Coordinator)
shona at ncbs dot res dot in

Ravi Muddashetty
ravism at instem dot res dot in

   

Archana Purushotham
archana at instem dot res dot in

Siddharthan Chandran

   

Peter Kind
p.kind at ed dot ac dot uk

Richard Morris
ccns at ed dot ac dot uk

   

Upinder Bhalla
bhalla at ncbs dot res dot in 

 David Wyllie

 

Center for Cardiovascular Biology and Disease

 

Center for Cardiovascular Biology and Disease collaborates with labs at Stanford, iCeMs Kyoto, JNCASR and NCBS to investigate inherited cardiomyopathies.

Jim Spudich(Coordinator)
Muscle biochemistry and biophysics
jspudich at stanford dot edu

John Mercer
Myosins
jam at instem dot res dot in

   

Kouichi Hasegawa
Stem Cell Biology
kouichih at instem dot res dot in

Maneesha Inamdar
Cardiovascular development and genetics
inamdar at jncasr dot ac dot in

   

R. Sowdhamini
Protein structure
mini at ncbs dot res dot in

Minhaj Sirajuddin
Structure And Function Of Cytoskeletal Assemblies
minhaj at instem dot res dot in

 

Centre for Chemical Biology and Therapeutics

 

Center for Chemical Biology and Therapeutics collaborates with researchers at Cambridge University to discover new chemical tools for signaling pathway regulation in cancer.
 

Ashok Venkitaraman(Coordinator)
Chemical Biology and Therapeutics
ashokv at ncbs dot res dot in

 

Joint Centre for Inflammation and Tissue Homeostasis

 

Center for Inflammation and Tissue Homeostasis collaborates with IFOM in Milan, Italy to investigate the interactions between the inflammatory response and other cells that restore or maintain tissues, with a focus on epithelia.
 

Colin Jamora(Coordinator)
Mechanisms regulating the wound healing response
colinj at instem dot res dot in

Srikala Raghavan
Structure And Function Of Cytoskeletal Assemblies
srikala at instem dot res dot in

   

Shravanti Rampalli-Deshpande
Epigenetics and Cell fate determination
shravantird at instem dot res dot in

Ramanuj DasGupta
ramanujd at instem dot res dot in

 

Regulation of Cell Fate

 

Apurva Sarin(Coordinator)
sarina at ncbs dot res dot in

Jyotsna Dhawan(Visiting Professor)
Quiescence and self-renewal
Jdhawan at instem dot res dot in

   

Tina Mukherjee
Metabolic And Systematic Control Of Stem Cell Development
Tinam at inStem dot res dot in

Sunil Laxman
Nutrient Sensing And Metabolic Regulation Of Cell Fates
sunil at inStem dot res dot in

 

Technologies for the Advancement of Science

 

echnologies for the Advancement of Science is a diverse interdisciplinary team that interacts across research themes to create innovative bespoke technologies for regenerative biology.
 

Ramaswamy S.(Coordinator)
Biochemistry and BioPhysics
ramas at instem dot res dot in

Norio Nakatsuji(Mentor)
Stem Cell Biology
nnakatsu at icems.kyoto-u.ac.jp

   

Akash Gulyani
Cellular dynamics
akashg at instem dot res dot in

Dasaradhi Palakodeti
Model systems to study regeneration
dasaradhip at instem dot res dot in

   

Jeff Abramson
Membrane Proteins
jabramson at mednet.ucla.edu

Kouichi Hasegawa
Stem Cell Biology
kouichih at ncbs dot res dot in

   

Praveen Kumar Vemula
Laboratory of Self-Assembled Biomaterials and Translational Research
praveenv at instem dot res dot in

Ramkumar Sambasivan
Gene regulatory networks, stem cells and development
ramkumars at instem dot res dot in

 

inStem is also home to the Shanta Wadhwani Centre, a generous philanthropic donation dedicated to the study of biology and disease in two critical systems-the brain and the heart.

 

 

 

Reach Us

Institute for Stem Cell Biology and Regenerative Medicine,
National Centre for Biological Sciences,
Tata Institute of Fundamental Research,
GKVK, Bellary Road,
Bangalore 560065, India.

Login